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KMID : 0545120090190121617
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Journal of Microbiology and Biotechnology
2009 Volume.19 No. 12 p.1617 ~ p.1619
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Production of c9, t11- and t10, c12-conjugated linoleic acids in humans by Lactobacillus rhamnosus PL60
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Lee Ki-Eun
Lee Yeon-Hee
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Abstract
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Lactobacillus rhamnosus PL60 was tested whether it can produce c9, t11- and t10, c12- conjugated linoleic acids (CLAs) in human. After consumption of L. rhamnosus PL60, L. rhamnosus was detected in feces 1 week after the start of intake. Analysis by gas chromatography showed that concentrations of c9, t11- and t10, c12-CLAs in serum had increased and concentrations of serum leptin had significantly decreased. Results showed that L. rhamnosus PL60 can survive in human intestines and produce CLAs in human. This is the first report that bacteria can produce CLAs in human.
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KEYWORD
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Conjugated linoleic acid, Lactobacillus rhamnosus, anti-obesity
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